F. MR image denoising

High resolution mapping of MRI T2 relaxation times can benefit many clinical applications by offering improved anatomic details, enhancing the ability to assess tissue architecture and identify early pathology. Increasing the spatial resolution while leaving the rest of the scanning parameters unchanged, however, causes major decrease of signal-noise-ratio (SNR). This impairs the quality of the resulting images and the accuracy of the ensuing radiological interpretation, whether qualitative or quantitative. In this project we are testing the utility of PCA-based complex image denoising for improving quality of T2 mapping from rapid multi echo spin-echo data. Shown here are original and denoised T2-weighted images and T2 maps from two different high resolution brain scans.

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